Hello!
Unfortunately not.
First example, Mini MEVD17.2.3
Car has manual gear, DME is from a car with automatic gear system (8HP). You can flash the DME up and down, to the left or to the right, whatever you like, the car will not start and ISTA shows the error "no message from EGS - sender EGS, reciever DME". Problem was solved after I got a D-flash from a DME with manual transmission.
Now the MEVD1.2.G
Also the same. Car is a 335i with manual gear, got a new engine from a M3, donor DME came from a car with DKG. No way to start the car, always errors due to the missing EGS - also after flashing and coding the DME (with autohex and E-Sys). I loaded the D-Flash from the 335i into the M3 DME (both engines are using the same DME version - MEVD17.2.G) and the car started but not with full power (Variantenüberwachung). If you load the D-Flash from the M3 with DKG - nothing, car will not start. ISN and so on is correct, it's only a question of the transmission.
It looks like a one-way ticket. You can switch the DME from manual to automaric gear and it will work but not back to manual.
CU Oliver